# Heartburn at 28 Weeks Pregnant

Source: https://www.pregnancypowerhour.com/pregnancy/symptoms/heartburn-week-28
Last updated: 2026-07-01

> At 28 weeks pregnant, heartburn often becomes more pronounced as your growing uterus presses upward, intensifying discomfort, especially when lying flat.

At 28 weeks pregnant, the familiar sensation of heartburn often becomes a more noticeable companion, largely due to your growing uterus beginning to press upward on your stomach. This stage, deep into the third trimester, is when many expecting parents find heartburn symptoms peaking, affecting a significant portion of pregnancies. It's a common experience, and understanding why it's happening can bring a sense of clarity and calm.

The underlying reasons for heartburn during pregnancy are twofold. Firstly, the hormone progesterone, essential for maintaining your pregnancy, also has a relaxing effect on smooth muscles throughout your body. This includes the lower esophageal sphincter, the valve between your esophagus and stomach. When this valve relaxes, stomach acid can more easily flow back up, creating that burning sensation. Secondly, and particularly relevant at 28 weeks, your uterus is now quite large and continuing its upward expansion. This physical pressure on your stomach can contribute significantly to the reflux, making it feel more intense than earlier in pregnancy. You might notice this sensation is particularly bothersome when you're lying flat, as gravity is no longer helping to keep stomach contents down.

Navigating these physical changes can sometimes feel overwhelming, but there are practical, evidence-based approaches to finding relief. Many people find that simple adjustments can make a real difference in managing this discomfort. For some, it might be about understanding the nuances of how their body is changing, much like learning to adjust to other common physical shifts. For instance, while heartburn is a digestive discomfort, it's a different experience than, say, the changes you might notice with [Yeast Infection Symptoms in Pregnancy at 12 Weeks Pregnant](/pregnancy/symptoms/yeast-infection-symptoms-week-12), which can also become more common during pregnancy. The key is to approach each symptom with informed curiosity and a collaborative spirit with your care team.

When considering options for relief, it's helpful to know what is generally considered safe and effective. Over-the-counter calcium carbonate antacids, like Tums or Rolaids, are often the first line of defense and are considered safe across all trimesters. If these don't provide enough relief, your provider might suggest other options. For example, famotidine (Pepcid) is generally considered safe when antacids alone aren't sufficient. In some cases, for more persistent symptoms, omeprazole and other proton pump inhibitors (PPIs) are also generally considered safe during the second and third trimesters. Remember, these are options to discuss with your healthcare provider, who is your best resource for personalized guidance. Just as you might explore different strategies for managing other common pregnancy experiences, such as those related to [Yeast Infection Symptoms in Pregnancy at 10 Weeks Pregnant](/pregnancy/symptoms/yeast-infection-symptoms-week-10) or [Yeast Infection Symptoms in Pregnancy at 14 Weeks Pregnant](/pregnancy/symptoms/yeast-infection-symptoms-week-14), managing heartburn is about finding what works best for your unique situation, always in consultation with your medical team.